Sosei R&D Ltd.

Capital	JPY 182,737,452
Scope of business	Licensing and business development outside Japan
Representative Director	Peter Bains
Holding company stake	100%
Address	North West House, 119 Marylebone Road, London, United Kingdom (map) Tel: +44-(0)20-3965-6801

Heptares Therapeutics Ltd.

Capital	JPY 45,525,238
Scope of business	Drug discovery based on targeting of G protein-coupled receptors
Representative Director, CEO	Malcolm Weir, CEO
Holding company stake	100%
Address	BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire, AL7 3AX, UK (map)
URL	www.heptares.com

Jitsubo Co. Ltd.

Capital	JPY 100,000,000
Scope of business	Development of peptide drugs, licensing of peptide API manufacturing technology
Representative Director, CEO, and CTO	Kazuaki Kanai
Holding company stake	43.7%
Address	Life Science Research Center 4-1 1-1-43 Suehiro-cho, Tsurumi, Yokohama 230-0045, Japan
URL	www.jitsubo.com/en/

Sosei Co. Ltd.

Capital	JPY 250,000,000
Scope of business	Drug development and sales, business development in Japan
Representative Director	Tadayoshi Yasui
Holding company stake	100% (voting rights)
Address	PMO Hanzomon 11F 2-1 Kojimachi, Chiyoda-ku Tokyo 102-0083 Japan (map) Tel: +81-(0)3-5210-3290 (general enquiries) Fax: +81-(0)3-5210-3291

Sosei CVC Ltd.

Capital	JPY 10,000,000
Scope of business	Managing Sosei RMF1 (Regenerative Medicine Fund)
Representative Director	Peter Bains
Holding company stake	90%
Address	PMO Hanzomon 11F 2-1 Kojimachi, Chiyoda-ku Tokyo 102-0083 Japan (map) Tel: +81-(0)3-6679-2044 (general enquiries) Fax: +81-(0)3-5210-3291