Sosei R&D Ltd.

Capital	JPY 182,737,452
Scope of business	Licensing and business development outside Japan
Representative Director	Shinichi Tamura
Holding company stake	100%
Address	2nd Floor, London BioScience Innovation Centre 2 Royal College Street London NW1 0NH, United Kingdom (map) Tel: +44-(0)20-7691-2081 Fax: +44-(0)20-7209-2484

Heptares Therapeutics Ltd.

Capital	JPY 45,525,238
Scope of business	Drug discovery based on targeting of G protein-coupled receptors
Representative Director, CEO	Malcolm Weir, CEO
Holding company stake	100%
Address	BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire, AL7 3AX, UK (map)
URL	www.heptares.com

Activus Pharma Co., Ltd.

Capital	JPY 97,800,000
Scope of business	Drug development based on nanotechnology (APNT)
Representative Director	Tadayoshi Yasui
Holding company stake	100%
Address	1-17-25 Kita-honcho, Funabashi-shi, Chiba 273-0864 Japan

Jitsubo Co. Ltd.

Capital	JPY 100,000,000
Scope of business	Development of peptide drugs, licensing of peptide API manufacturing technology
Representative Director	Yusuke Kohno
Holding company stake	43.7%
Address	2-24-16 Nakacho, Koganei, Tokyo 184-0012, Japan
URL	www.jitsubo.com/en/

Sosei Co. Ltd.

Capital	JPY 250,000,000
Scope of business	Drug development and sales, business development in Japan
Representative Director	Tadayoshi Yasui
Holding company stake	100% (voting rights)
Address	Kojimachi Tsuruya Hachiman Bldg. 5F 2-4 Kojimachi, Chiyoda-ku Tokyo 102-0083 Japan (map) Tel: +81-(0)3-5210-3290 (general enquiries) Fax: +81-(0)3-5210-3291

Sosei CVC Ltd.

Capital	JPY 10,000,000
Scope of business	Managing Sosei RMF1 (Regenerative Medicine Fund)
Representative Director	Peter Bains
Holding company stake	90%
Address	Kojimachi Tsuruya Hachiman Bldg. 5F 2-4 Kojimachi, Chiyoda-ku Tokyo 102-0083 Japan (map) Tel: +81-(0)3-5210-3290 (general enquiries) Fax: +81-(0)3-5210-3291